![Image of Petri dishes](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Petri_dishes_wide.jpg?h=26b29af5&itok=p3BGVBYc)
Allen lab
Allen lab focuses on understanding the basic science mechanisms by which pharmacological ascorbate can selectively act as a pro-oxidant in brain and lung cancer vs. normal cells.
![Brett and the Seahorse](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Brett_Seahorse.jpg?h=539cc07a&itok=goaEgFEy)
Buettner lab
The use of the ascorbate radical as a marker for free radical oxidative stress. This research has provided the foundation for many ongoing free radical-related research projects.
![GEM foam from a whippet dispenser](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/GEM%20foam.png?h=96cdf707&itok=zwhRsTDA)
Byrne lab
Byrne Lab is driven by our long-term interest: developing transformative technologies to improve patient care. Bridging the disciplines of biomedical engineering and oncology, our lab strives toward innovation.
![Ben George performing assay](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Ben%20George.jpg?h=a1b95d11&itok=08fvMdgp)
Caster lab
The overarching theme of our research is to identify novel ways of improving the therapeutic index of chemoradiotherapy; i.e. improving treatment the efficacy of chemoradiation and/or minimizing its toxicity.
![Image from a confocal microscope](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Confocal_image.jpg?h=b234cc96&itok=Dq8mBgP7)
Coleman lab
The Coleman laboratory conducts translational research focused on prevention of musculoskeletal disorders that result from injury, whether after a car crash or exposure to therapeutic doses of radiation.
![Screenshot of Cullen Pancreatic cancer article](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Cullen_ASC.png?h=d8a3adf2&itok=9MNFXUiw)
Cullen lab
Currently, the lab focuses on multiple avenues for the utilization of pharmacological ascorbate in the treatment of pancreatic adenocarcinoma.
![Screenshot of Goswami lab research article](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Goswami_research.png?h=ba045b8c&itok=Em1z1XWX)
Goswami lab
Dr. Goswami's laboratory is pursuing basic science research in the field of free radical biology and chemistry of the mammalian cell cycle, aging and cancer.
![Researcher weighing cells on scale](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Sanne_weighing_cells.jpg?h=7d56d2d3&itok=LfmZCgsl)
Griguer lab
Our lab was among the first to describe the importance of mitochondrial respiratory complexes on tumor growth and resistance to therapy.
![Howard lab personnel](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Howard_lab_June24.jpg?h=d2abe872&itok=E85kss8f)
Howard lab
Howard Lab aims to increase the therapeutic ratio of conventional radiotherapy by utilizing therapeutic agents to sensitize tumors and protect normal tissues for improved clinical outcomes in pediatric brain cancer patients.
![Screenshot of Mike Schultz's research](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Schultz_screenshot.png?h=a92f03cd&itok=rvD_JfE0)
Schultz lab
Dr. Schultz’s lab focuses on tumor cell biology, radiation biology, peptide based ligand development, and radiochemistry for the development of image-guided radionuclide based therapies for cancer.
![Ann Simons-Burnett lab personnel](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Simons-Burnett-lab.jpg?h=270264b5&itok=WzKXulia)
Simons-Burnett lab
Our laboratory seeks to enhance the treatment of head and neck cancer by improving radiotherapy and chemotherapy regimens for recurrent and metastatic disease.
![Portrait of Doug Spitz and his lab](/sites/radiationoncology.medicine.uiowa.edu/files/styles/widescreen__1024_x_576/public/2024-09/Spitz_lab_52_s.jpg?h=1c15f69f&itok=gV44CKhT)
Spitz lab
A central theme of these interdisciplinary studies are focused on the role of free radicals and redox stress in cancer biology from both the basic science as well as a pre-clinical and clinical translational perspectives.